• Home
    • What we do
    • About TLS
    • TLS Privacy Policy
    • Contact
    • Case Studies
  • Laminitis
    • Emergency Treatment
    • Chronic laminitis
    • Laminitis FAQ
  • EMS/ID
    • Management strategies for EMS/ID
    • EMS/ID FAQ
    • Rosie
  • Diet
    • Diet FAQ
  • PPID
    • PPID FAQ
    • Half Pint
    • Widget
  • Feet
    • Realigning Trim
    • Feet A-Z
    • Chronic laminitis
    • Understanding x-rays
    • Taking hoof photos
    • Feet FAQ & Articles
    • Feet gallery
    • Reading the foot
    • Dorsal rotation/long toes
    • High heels
    • Palmar Angle Calculator
    • Sorrel
    • Monroe
    • Cedar
  • News
  • Articles
  • A-Z
    • A
    • B
    • C
    • D
    • E
    • F
    • G
    • H
    • I
    • J K
    • L
    • M
    • N
    • O
    • P Q
    • R
    • S
    • T
    • U V W X Y Z
  • Case Studies
    • Danae
    • Half Pint
    • Herbie
    • Herbie diary
    • Herbie's TTouch diary
    • Izmir
    • Misty
    • Nero
    • Nutmeg
    • Nutmeg TLS rehab
    • Rosie
    • Sorrel
    • Tex
    • Widget
  • France
    • Articles en francais
  • Research
    • New Research/Research by Date
    • Research papers by subject
    • Research papers by author
    • Research news/comment
    • Research projects >
      • NSC in grass & hay
      • How much do horses eat?
      • Do fructans cause laminitis?
      • Turmeric/Curcumin
      • Insulin response to diet
    • Help with research
  • Help!
    • Join Friends of TLS
    • Donate
    • Appeals
    • Raise funds for TLS
    • In Loving Memory
    • Friends of TLS only
The Laminitis Site

How accurate is blood testing for PPID?

9/3/2021

1 Comment

 

Meyer JC, Hunyadi LM, Ordóñez-Mena JM
The accuracy of ACTH as a biomarker for Pituitary Pars Intermedia Dysfunction in horses: A systematic review and meta-analysis
Equine Vet J. 2021 Aug 24. doi: 10.1111/evj.13500. Epub ahead of print. PMID: 34428330

Conclusions: !"In horses with a high pre-test probability of PPID, ACTH may be a functional "rule-in" test. Baseline ACTH is not recommended for screening purposes or use in horses without clinical signs of PPID."
See also A Systematic Review and Meta-analysis on the diagnosic accuracy of baseline ACTH for the diagnosis of PPID in adult horses and ponies by James Meyer 4th Global Equine Endocrine Symposium 2020 p8
Conclusions: "​The overall results and those in the reference standard subgroup of histopathology suggest that the specificity of baseline ACTH for the diagnosis of PPID is good while the sensitivity is marginal (lower CI 57%).  This would corroborate the current recommendation that baseline ACTH be used as a triage test for PPID with further diagnostics being recommended in patients that test negative."
​


1 Comment

    Articles


    How accurate is blood testing for PPID?

    Obtaining Bova pergolide paste
    Treating PPID
    FDA New Animal Drug Application for Prascend September 2011
    ​Free ACTH Testing
    ​PPID and laminitis ​
    ​
    PPID - findings at post mortem
    PPID and breeding
    ​ACTH interpretation
    ​
    PPID and Parkinson's Disease
    Incidence of PPID
    ​
    Should I seasonally alter the dose of Prascend...?
    ​​How should pergolide /Prascend be introduced?
    ​What is PPID?
    Pituitary stress hormones
    Does a high ACTH result mean my horse has PPID?
    What causes PPID?
    Can any horse get PPID?
    Temperament changes with PPID/pergolide

    Archives

    September 2021
    March 2021
    November 2020
    August 2019
    April 2018
    December 2017
    October 2017
    September 2017
    June 2017
    May 2017
    August 2016
    June 2016
    June 2015
    May 2015
    December 2013

    RSS Feed

Laminitis/EMS/PPID? Start here
Need help/support? Join FoTLS
Donate to help laminitic horses
Disclaimer: The information, suggestions and links (hereafter referred to as “information”) contained in this website are provided for information purposes only and should not be relied upon nor replace professional veterinary advice.  Information is non-veterinary, is based as far as possible on current research, does not constitute advice or diagnosis, and should be discussed in full with all relevant vets and hoofcare or other professionals.  No responsibility is taken for the accuracy or suitability of information contained in this website, and no liability accepted for damages of any kind arising from use, reference to or reliance on any information contained in this website.  If you suspect your horse has laminitis or is ill, please consult your vet. 
The Laminitis Site is a charitable company registered in England & Wales No. 8530292, recognized by HMRC as a charity for Gift Aid.  
Please consider making a donation to support the work of The Laminitis Site.
For more information and membership of the TLS support/discussion group, join Friends of The Laminitis Site.
The Laminitis Site's Privacy Policy.