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The Laminitis Site

R

Radiographs (x-rays)
Regional Limb Perfusion
Resection - of hoof wall
​Resveratrol
Retained Placenta
RISQI
​

 

Radiographs (x-rays)

Radiographs should always be taken when a horse has had laminitis.

See Understanding x-rays/radiographs

Radiograph technique

Use digital radiographs (see below) if at all possible.
Thoroughly clean and ideally trim the foot.
Always place a radiodense marker (a clench or length of straight wire will do - it can be taped on) on the dorsal hoof wall (i.e. at the toe) extending right to the coronary band/hair line (although digital radiographs are very clear, without this marker it is almost impossible to accurately assess sinking)
A radiodense marker (a sawn-off drawing pin is ideal) can be placed just back from the apex of the frog - this is particularly useful if the horse is likely to be shod with frog support.
The horse will need to stand on a wooden block and should be weight bearing, therefore either the leg not being x-rayed should be held up, or both (e.g.front) legs should be on blocks.
Centre beam 1-2 cm above the block in the middle of the foot
It is conventional for markers to be placed on the dorsal or lateral aspect of the foot or limb (this is particularly important for DP views).

Lateral-medial radiographs of P3 help assess rotation and sinking.
Dorsopalmar radiographs of P3 can be helpful in assessing lateral-medial hoof imbalance

Equine Radiography: Positioning Techniques & Tips for Acquiring Good Images - Shalyn J Crawford 2015

Front and Hind Limb Radiology - Christina Garloff May 2012

Explaining Laminitis and its Prevention - Robert Eustace: X-ray technique

Laminitis Radiology - Chris Pollitt

The Phalanges

Radiology of the Equine Limbs

Radiography - John the Vet

Radiographic Examination of the Equine Foot - W Rich Redding

Radiography and radiology of the equine foot - R Weller - 50th BEVA Congress 2011

O'Brien's Radiology for the Ambulatory Equine Practitioner - Timothy R O'Brien (2005)

Equine distal limb normal radiographic anatomy - Karl L Anderson  University of Minnesota

Atlas of Diagnostic Radiology of the Horse - Diseases of the Front and Hind Limbs -  Kees J. Dick and Ilona Gunsser

The Value of Quality Foot Radiographs and Their Impact on Practical Farriery - Randy Eggleston, AAEP 2012

Can Hoof Wall Radiographs Help Identify Early Laminitis? - Casie Bazay, www.thehorse.com, Dec 2015

​Sherlock C, Parks A
Radiographic and radiological assessment of laminitis
Equine Veterinary Education October 2013 Vol 25, Issue 10 Pages 524-535 (Full)

​Collins SN, Dyson SJ, Murray RC, Newton JR, Burden F, Trawford AF
Development of a quantitative multivariable radiographic method to evaluate anatomic changes associated with laminitis in the forefeet of donkeys
Am J Vet Res. 2012 Aug;73(8):1207-18. doi: 10.2460/ajvr.73.8.1207

Eggleson RB
Value of Quality Foot Radiographs and Their Impact on Practical Farriery
AAEP Proceedings 2012 Vol. 58

Baker WR Jr
Treating laminitis: beyond the mechanics of trimming and shoeing
Vet Clin North Am Equine Pract. 2012 Aug;28(2):441-55. doi: 10.1016/j.cveq.2012.05.004
"The use of radiographs for diagnosis and interpretation of laminitis is an absolute necessity..."
Radiographs are useful for diagnosis, prognosis and to guide treatment.  Lateral views should be taken with both feet on equal height blocks and the main beam focused at the solar margin of P3, with the foot touching the casette to avoid magnification.  Variation from the correct technique will result in artifacts and false information.  It is essential to mark the dorsal hoof wall and frog apex, e.g. with barium paste.  Useful measurements include the coronary/extensor distance, sole depth, the horn:lamellar distance, and the palmar angle.  The dorsal angle is not (particularly) important, and is influenced by deformity of the outer wall. 

Page BT, Bowker RM, Ovnicek G, Hagen TL
How to Mark the Foot for Radiography
AAEP Proceedings 1999 Vol 45


Picture
Film radiograph
Picture
Digital radiograph
Film v digital radiographs.  2 x-rays taken of the same horse, left fore, a few days apart, following acute laminitis.  From the film x-ray on the left the first vet diagnosed 4' rotation.  From the digital x-ray on the right taken a few days later the second vet diagnosed no rotation.
The x-ray on the left is an example of a bad x-ray - no markers were used, the horse was not weight bearing, the whole hoof is not shown therefore the relationship of P3 to the hoof capsule cannot be seen.
The x-ray on the right is an example of a good x-ray - markers positioned correctly and can be used for scale measurements, the horse was weight bearing, the relationship of P3 to the well balanced hoof capsule is clearly shown, the x-ray beam was perpendicular to the hoof.
These x-rays cost much the same!  Always ask for digital x-rays, ideally where the x-rays are processed on site - if your vet does not have suitable equipment, they should be able (and happy) to recommend another vet who does.

 

Regional Limb Perfusion (RLP)


Regional Limb Perfusion is the administration of antibiotics directly into an affected leg, and allows much higher levels of antibiotics to reach infected tissues compared to other methods of delivering antibiotics.  RLP may be particularly useful in cases of localized bone infections such as osteomyelitis.  
Bacterial culture should guide the choice of antibiotics.  A tourniquet is used above the infection site, and a high dose of antibiotics delivered into the blood supply below the tourniquet.  Several RLP treatments will usually be required.

​Subsolar Abscess and Coffin Bone Osteomyelitis - ACVS ​

How to perform a regional limb perfusion in horses - Amy Poulin Braim - DVM360 Mar 2015 

Cimetti LJ, Merriam JG, D'Oench SN
How to Perform Intravenous Regional Limb Perfusion Using Amikacin and DMSO
AAEP Annual Convention 2004

1999 Vol. 45 AAEP PROCEEDINGS
How to Perform Regional Limb Perfusion in the Standing Horse
Scott E. Palmer, VMD; and Patricia M. Hogan, VMD

1998 Vol. 44 AAEP PROCEEDINGS
How to Perform Equine Intravenous Digital Perfusion
E. M. Santschi, DVM; S. B. Adams, DVM, MS; and E. D. Murphey, DVM


 
Resection - of hoof wall

Rucker A
Chronic laminitis: strategic hoof wall resection
Vet Clin North Am Equine Pract. 2010 Apr;26(1):197-205. doi: 10.1016/j.cveq.2009.12.009


Before considering a hoof wall resection, please read Dr Debra Taylor's presentation Laminitis Rehabilitation: If the corium is happy, there is hope.  Have venograms taken, re-establish perfusion by minimizing mechanical compression and stretching of the corium within the hoof capsule.  To reduce coronary corium compression, remove ground reaction force from the associated hoof wall at ground level, e.g. by beveling the hoof or dubbing the toe.  Solar corium compression can be reduced by creating an air space beneath the rim of P3 (e.g. using thick pads inside hoof boots) and correcting the palmar angle.  If this is insufficient to improve perfusion, higher level interventions to minimize compression may be considered, such as hoof grooving or partial hoof wall resection.

 
Resveratrol

​
Manfredi JM, Stapley ED, Nadeau JA, Nash D
Investigation of the effects of a dietary supplement on insulin and adipokine concentrations in equine metabolic syndrome/
insulin dysregulation

Journal of Equine Veterinary Science published online Jan 2020. doi.org/10.1016/j.jevs.2020.102930

Non-Drug Treatments for Equine Metabolic Syndrome - Dr Vern Dryden & Dr Amanda Adams, www.thehorse.com 2018

Resveratrol - Equithrive
NB product claims that are not backed by published research are claims, not research.


 
Retained placenta
 
Retention of any part of the placenta after foaling (or still birth) can lead to bacterial growth, inflammation and absorption of toxins, which can cause endotoxaemia, septicaemia, metritis, sepsis related laminitis (SRL) and death.  Every part of the placenta should be removed, and the horse treated with systemic antibiotics and anti-inflammatories, and measures taken to prevent laminitis e.g. cyrotherapy.  

Equine placenta – marvelous organ and a lethal weapon - Malgorzata Pozor (2013) - page 9 onwards

Current Therapy in Equine Reproduction - edited by Juan C. Samper, Jonathan F. Pycock, A. O. McKinnon (2007) p 465
​

 

RISQI

RISQI is the reciprocal of the square root of insulin, and represents the degree of insulin sensitivity (the higher the number, the more insulin sensitive).

RISQI is calculated: 1 divided by the square root of the baseline insulin result.  So if a horse's fasting baseline insulin is 9 µIU/ml, the square root of 9 is 3, and 1/3 is 0.333.  According to the Virginia Polytechnic research below, a RISQI of 0.333 would be normal, not IR.  A fasting baseline insulin of 25 µIU/ml would give a RISQI of  0.20 (the square root of 25 is 5, 1/5 = 0.2), which according to the Virginia Polytechnic research below would indicate a high laminitis risk. 

The use of the RISQI is not recommended by some vets - see Proxies and forum. 

IR calculator - enter your horse's glucose and insulin blood results and the G:I ratio, RISQI, MIRG and IR status is calculated for you.

Virginia Polytechnic RISQI:
RISQI > 0.32 = normal
RISQI < 0.32 = laminitis risk
RISQI < 0.22 = high laminitis risk
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