Do all horses with PPID have an increased risk of laminitis?
No. The laminitis associated with PPID is endocrine laminitis, due to insulin dysregulation (insulin resistance and/or hyperinsulinaemia). Horses with PPID may or may not have insulin dysregulation (ID). If they do not have ID, their laminitis risk is considered to be normal.
Mastro LM, Adams AA, Urschel KL
Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses
Domest Anim Endocrinol. 2015 Jan;50:14-25. doi: 10.1016/j.domaniend.2014.07.003. Epub 2014 Aug 1
"The results from this study provide evidence that PPID is not always associated with impairments in insulin sensitivity."
Mastro Laurel M 2013 University of Kentucky MSc thesis
The effect of Pituitary Pars Intermedia Dysfunction on Protein Metabolism and Insulin Sensitivity in Aged Horses
No. The laminitis associated with PPID is endocrine laminitis, due to insulin dysregulation (insulin resistance and/or hyperinsulinaemia). Horses with PPID may or may not have insulin dysregulation (ID). If they do not have ID, their laminitis risk is considered to be normal.
Mastro LM, Adams AA, Urschel KL
Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses
Domest Anim Endocrinol. 2015 Jan;50:14-25. doi: 10.1016/j.domaniend.2014.07.003. Epub 2014 Aug 1
"The results from this study provide evidence that PPID is not always associated with impairments in insulin sensitivity."
Mastro Laurel M 2013 University of Kentucky MSc thesis
The effect of Pituitary Pars Intermedia Dysfunction on Protein Metabolism and Insulin Sensitivity in Aged Horses
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