Significantly, according to an example given by Andy Durham in his 2008 paper The effect of metformin ... (see below), in which one horse had a fasting resting insulin at the start of the research (presumably without clinical laminitis) of 32.8 miu/l, and a fasting resting insulin after 220 days of Metformin treatment and a recurrence of clinical laminitis of 377.5 miu/l.
Factors that may affect insulin levels include:
pain, illness, PPID, excitement, stress, recent exercise, recent eating/length of fasting, obesity, genetics, fitness, time of day, time of year, reproductive status, age and environmental temperature.
Equine Vet J. 2008 Jul;40(5):493-500
The effect of metformin on measurements of insulin sensitivity and beta cell response in 18 horses and ponies with insulin resistance.
Durham AE, Rendle DI, Newton JE.
Factors that may affect insulin levels include:
pain, illness, PPID, excitement, stress, recent exercise, recent eating/length of fasting, obesity, genetics, fitness, time of day, time of year, reproductive status, age and environmental temperature.
Equine Vet J. 2008 Jul;40(5):493-500
The effect of metformin on measurements of insulin sensitivity and beta cell response in 18 horses and ponies with insulin resistance.
Durham AE, Rendle DI, Newton JE.
